Should some hallucinogenic drugs be legalized for use in Massachusetts? That is what Question 4 asks Bay State voters to decide.

If approved, the measure would allow five psychedelics — psilocybin, psilocyn, mescaline, dimethyltryptamine (also known as DMT, the psychoactive ingredient in the drug ayahuasca) and ibogaine — to be grown, shared, used at home and offered by licensed professionals in a clinical setting. It would also create a commission to regulate those substances.

Advocates ...