A “yes” vote on this question would allow a group of naturally occurring psychedelic drugs — psilocybin, psilocyn, mescaline, dimethyltryptamine (DMT), and ibogaine — to be grown, shared and used at home, as well as by licensed professionals in a clinical setting, according to the Tufts analysis.

Advocates have touted the benefits of the substances when it comes to treating anxiety and other disorders, The Republican newspaper of Springfield, reported in September.

There are concerns, however, about the health harms associated with psychedelic substances. For instance, “ibogaine can cause acute cardiac problems, while DMT (used in ayahuasca) may have lasting neurological effects,” the Tufts analysis noted.