Dana Beal – Nerve Growth Factor GDNF Elucidates Ibogaine’s Persistence & Immune Modulatory Effects

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Ibogaine shares receptor effects with both Salvia divinorum (κ-opiate down-regulation of tolerance via beta-arrestin) and with ketamine (NMDA antagonism, curbing narcotic withdrawal and super-sensitization to stimulants). Additionally, ibogaine induces the nerve growth factor GDNF (Glia-Derived Neurotrophic Factor), re-sprouting chronically desensitised dopamine receptors and replacing the neural deficit experienced as craving. Moreover, the 10-fold GDNF spike engendered by ibogaine back-signals to cell nuclei to make more GDNF, setting ...

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Mechanisms of Action of Ibogaine (PART 2)

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Excerpt from the 2010 ICEERS Ibogaine Conference held at the Catalan Health Ministry.

Presentation by Kenneth R. Alper, M.D.
Visit www.iceers.org for more info.

source

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Mechanisms of Action of Ibogaine (PART 1)

Posted by:



Excerpt from the 2010 ICEERS Ibogaine Conference held at the Catalan Health Ministry.

Presentation by Kenneth R. Alper, M.D.
Visit www.iceers.org for more info.

source

Continue Reading →
0
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